Related Products of 1539-42-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1539-42-0, name is Bis(pyridin-2-ylmethyl)amine. This compound has unique chemical properties. The synthetic route is as follows.
1-Chloro-4-iodo-2-trifluoromethylbenzene (10 mmol) obtained in Reaction 1.2Dissolved in 20 ml of toluene, bis(pyridyl-2-methyl)amine (12 mmol), palladium acetate (0.5 mmol), 2,2′-bis(diphenylphosphino)-1,1 ‘-Binaphthyl (12 mmol), 3 ml of triethylamine, after stirring for 10 minutes, add 10 ml of an aqueous solution of cesium carbonate (10 mmol), and heat to 50 C for 4 hours. After the reaction, add 20 ml of water to the system. After stirring for 20 minutes, the organic layer was dried over anhydrous sodium sulfate, concentrated, and purified by flash column chromatography Fluoromethylaniline powder, yield 87.5%.
According to the analysis of related databases, 1539-42-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Jingfan; Jing Fan; Ge Baoyin; Zhang Ruwei; (8 pag.)CN108530342; (2018); A;,
Pyridine – Wikipedia,
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