In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1033203-41-6, name is 6-Bromopyridine-3,4-diamine, the common compound, a new synthetic route is introduced below. Recommanded Product: 6-Bromopyridine-3,4-diamine
To a stirred solution of 6-bromopyridine-3,4-diamine (1.5 g, 8 mmol) in triethylorthoformate (7.11 g, 48 mmol) was added acetic anhydride (7.35 g, 72 mmol)) and stirred at 90C for 6h. The reaction mixture was cooled and evaporated to dryness, then 10 mL 10N NaOH solution was added and heated the contents at 60 C for 50 min. After reaction mixture was cooled acidified with AcOH to a pH 6, then added crushed ice stirred for 15 minutes precipitated solid was filtered. The precipitated solid was washed with n-pentane to get 6-bromo-3H- imidazo[4,5-c]pyridine (1.5 g, 94%) as pale brown solid. LC-MS (method 32): Rt = 0.26 min; m/z = 198.0 (M+H+).
The synthetic route of 1033203-41-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ORYZON GENOMICS, S.A.; SALAS SOLANA, Jorge; CARCELLER GONZALEZ, Elena; ORTEGA MUNOZ, Alberto; (195 pag.)WO2018/149986; (2018); A1;,
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