New downstream synthetic route of 72141-44-7

The chemical industry reduces the impact on the environment during synthesis 72141-44-7, I believe this compound will play a more active role in future production and life.

Reference of 72141-44-7, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.72141-44-7, name is 4-Chloro-2-methoxypyridine, molecular formula is C6H6ClNO, molecular weight is 143.5709, as common compound, the synthetic route is as follows.

EXAMPLE 13 1-(2-methoxypyridin-4-yl)-4-[4-[[7-(trifluoromethyl)-4-quinolinyl]amino]benzoyl]piperazine In the manner given in Example 5, a mixture of 4-[4-[[7-(trifluoromethyl)-4-quinolinyl]amino]benzoyl]piperazine, 4-chloro-2-methoxypyridine and triethylamine is heated in ethylene glycol at 80 C. to give 1-(2-methoxypyridin-4-yl)-4-[4-[[7-(trifluoromethyl)-4-quinolinyl]amino]benzoyl]piperazine.

The chemical industry reduces the impact on the environment during synthesis 72141-44-7, I believe this compound will play a more active role in future production and life.

Reference:
Patent; The Upjohn Company; US4167567; (1979); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem