Introduction of a new synthetic route about 2-Fluoro-3-nitro-5-methylpyridine

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 19346-44-2, 2-Fluoro-3-nitro-5-methylpyridine, other downstream synthetic routes, hurry up and to see.

Application of 19346-44-2, Adding some certain compound to certain chemical reactions, such as: 19346-44-2, name is 2-Fluoro-3-nitro-5-methylpyridine,molecular formula is C6H5FN2O2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 19346-44-2.

[0261] A solution of ferf-butyl piperazine-l -carboxylate (7.75 g, 41.6 mmol), 2-fluoro-5- methyl-3-nitropyridine (5 g, 32.0 rnmol) and K2CO.3 (13.28 g, 96 mmol) in ACN (80 mL) was stirred at RT overnight. The reaction mixture was filtered with suction and the solvent removed under reduced pressure to give the title product which was used without further purification. -MS m/z [M+Hf 323.2.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 19346-44-2, 2-Fluoro-3-nitro-5-methylpyridine, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; TAKEDA PHARMACEUTICAL COMPANY LIMITED; GREEN, Jason; HOPKINS, Maria; JONES, Benjamin; KIRYANOV, Andre A.; KUEHLER, Jon; MONENSCHEIN, Holger; MURPHY, Sean; NIXEY, Thomas; SUN, Huikai; (300 pag.)WO2018/183145; (2018); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem