Adding a certain compound to certain chemical reactions, such as: 823-39-2, 3,4-Dimethylpyridin-2-amine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 823-39-2, blongs to pyridine-derivatives compound. COA of Formula: C7H10N2
Preparation M (3beta,5alpha,25R)3-trimethylsilyloxy-spirostan-11-one Silylation of Spirostanes Trimethylsilylchloride (3.27 mL, 25.8 mmol) was added to a solution of (3beta,5alpha,25R)3-hydroxy-spirostan-11-one (4.0 g, 9.3 mmol) and triethylamine (6.5 mL, 46 mmol) in dichloromethane (60 mL) at room temperature. One gram of dimethyl aminopyridine was added and the reaction was stirred at room temperature for 12 hours. The reaction was quenched with methanol (1 mL) and diluted with ethyl acetate, washed with water (5*) and brine (1*), dried (Na2 SO4), filtered and concentrated in vacuo. The product was triturated with methanol, filtered and dried to afford 3.94 g (85percent) product as a white solid. 1 H NMR (250 MHz, CDCl3) 6 4.5 (q, 1H, J=6Hz); 3.45 (m, 2H); 2.35 (t, 1H, J=10 Hz); 2.4 (dt, 1H, J=12.2 Hz); 2.2 (s, 2H); 2.1-1.1 (m, 12H); 1.02 (s, 3H); 0.9 (d, 3H, J=7.0 Hz); 0.78 (d, 3H, J=7 Hz); 0.69 (s, 3H); 0.1 (s, 9H).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,823-39-2, its application will become more common.
Reference:
Patent; Pfizer Inc.; US5939398; (1999); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem