Related Products of 122306-01-8, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.122306-01-8, name is (6-Bromopyridin-3-yl)methanol, molecular formula is C6H6BrNO, molecular weight is 188.02, as common compound, the synthetic route is as follows.
Reference Example 16; 2-bromo-5-(chloromethyl)pyridine hydrochloride 2-Bromo-5-(hydroxymethyl)pyridine (2.64 g) was dissolved in THF (70 mL) and, after ice-cooling, thionyl chloride (5.11 mL) was added dropwise. The reaction mixture was stirred at the same temperature for 30 min, and concentrated. The obtained residue was washed with diethyl ether to give the title compound (2.65 g) as yellow crystals.1H-NMR (CDCl3) delta: 4.55 (2H, s), 7.52 (1H, d), 7.63 (1H, dd), 8.40 (1H, d).
Statistics shows that 122306-01-8 is playing an increasingly important role. we look forward to future research findings about (6-Bromopyridin-3-yl)methanol.
Reference:
Patent; TAKEDA PHARMACEUTICAL COMPANY LIMITED; US2009/270359; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem