New downstream synthetic route of S-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl) ethanethioate

According to the analysis of related databases, 940943-37-3, the application of this compound in the production field has become more and more popular.

Related Products of 940943-37-3, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 940943-37-3, name is S-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl) ethanethioate, molecular formula is C20H25N3O5S2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

[0201] Into 0.3015 g of Compound 1 was added 1.0 molar equivalent of methanesulfonic acid (0.5 M in methanol) at 45 0C. The solids dissolved quickly upon stirring. The solution was allowed to cool slowly to ambient temperature. Light yellow solids were observed and obtained by vacuum filtration. The solids were left to air dry overnight (0.2959 g; yield 81%, based on unsolvated weight).

According to the analysis of related databases, 940943-37-3, the application of this compound in the production field has become more and more popular.

Reference:
Patent; KALYPSYS, INC.; WO2008/73733; (2008); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem