Synthetic Route of 947179-03-5, Adding some certain compound to certain chemical reactions, such as: 947179-03-5, name is Ethyl 4-bromo-6-methylpicolinate,molecular formula is C9H10BrNO2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 947179-03-5.
A solution of 4-bromo-6-methyl-pyridine-2-carboxylic acid ethyl ester (2.42 g, 9.91 mmol) in 6 N aq. HCI (100 ml_) is stirred at 65C for 18 h. The solvent is evaporated and the residue is dried under HV, suspended in DCM, filtered and dried again under HV to give 4-bromo-6-methyl-pyridine-2-carboxylic acid (2.50 g) as a hydrochloride salt in form of a white powder; LC-MS: tR = 0.46 min, [M+1]+ = 215.93.
According to the analysis of related databases, 947179-03-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ACTELION PHARMACEUTICALS LTD; WO2009/24905; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem