Related Products of 1060805-95-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1060805-95-9, name is 4-Chloro-6-methylnicotinic acid, molecular formula is C7H6ClNO2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Step 2: A mixture of 4-chloro-6-methyl-3-pyridinecarboxylic acid (10 g, 58.4mmol) and KMnO4 (27.7 g, 175.4 mmol) in H2O was reflux with stirring for 24 h. The mixture was cooled to temperature and filtrated. EtOH was added to the filtrate and filtrated again. The filtrate was concentrated by vacuo to give the crude product 17 g which was used directly to the next reaction without further purification.
According to the analysis of related databases, 1060805-95-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; GLAXOSMITHKLINE LLC; WANG, Yonghui; YU, Hongyi; WO2010/59552; (2010); A1;,
Pyridine – Wikipedia,
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