Related Products of 98027-84-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 98027-84-0, name is 2,6-Dichloro-4-iodopyridine. This compound has unique chemical properties. The synthetic route is as follows.
Intermediate Example 5. N-(6-chloro-4-(2,4-difluorophenyl)pyridin-2-yl)cycloprdpanesulfonamidea) 2,6-dichloro-4-(2,4-difluorophenyl)pyridineA solution of 2,6-dichloro-4-iodopyridine (1.5 g, 5.49 mmol) in 1,2-dimethoxy- ethane (15 ml) was degassed by N2 bubbling for 5 mm. 2,4-Difluorophenylboronic acid (0.86 g, 5.49 mmol, 1 eq) was added and the mixture was degassed for another 5 mm. Pd(dppf)C12 (0.358 g, 0.43 mmol, 0.08 eq) and aqueous sodium carbonate (1.45 g, 13.7 mmol, 2.5 eq) were added sequentially using the procedure of Intermediate Example 1 and the mixture was heated at 90 C for 16 h. The reaction mixture was quenched and extracted as in Intermediate Example 1. The solvent was distilled off to afford the cruderesidue which was purified by column chromatography (60-120 silica gel, 3 % ethyl acetate in hexane) to yield the title product in 98.5 % yield (1.4 g).
According to the analysis of related databases, 98027-84-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ORION CORPORATION; RAJAGOPALAN, Srinivasan; APPUKUTTAN, Prasad; NARASINGAPURAM ARUMUGAM, Karthikeyan; UJJINAMATADA, Ravi Kotrabasaiah; GEORGE, Shyla; LINNANEN, Tero; WO2014/162039; (2014); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem