Reference of 113118-82-4, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 113118-82-4, name is 5-Chloronicotinaldehyde. A new synthetic method of this compound is introduced below.
Hydroxylamine hydrochloride (2.3 g) and sodium acetate (2.7 g) were initially charged in ethanol (50 ml) under nitrogen (white suspension). 5-Chloronicotinaldehyde (4.3 g) were dissolved in ethanol (120 ml) (30 C., ultrasound bath) and added dropwise thereto within 15 minutes. The reaction mixture was stirred for 2 hours and concentrated at 40 C. Dichloromethane (550 ml) and water (250 ml) were added and the resulting precipitate is filtered off and dried. Yield: 2.1 g of 5-chloronicotinaldehyde oxime
At the same time, in my other blogs, there are other synthetic methods of this type of compound,113118-82-4, 5-Chloronicotinaldehyde, and friends who are interested can also refer to it.
Reference:
Patent; BAYER CROPSCIENCE AG; Frenzel, Thomas; Haaf, Klaus Bernhard; Lindell, Stephen David; Willms, Lothar; Dietrich, Hansjoerg; Schmutzler, Dirk; Gatzweiler, Elmar; Rosinger, Christopher Hugh; US2015/223461; (2015); A1;,
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