Application of 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine

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Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 72617-82-4, name is 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine. This compound has unique chemical properties. The synthetic route is as follows. category: pyridine-derivatives

EXAMPLE 8 1-(2,6-Dichlorobenzoyl)-3-(6-(2,2,2-Trifluoroethoxy)-3-Pyridinyl)Urea 2-(2,2,2-Trifluoroethoxy)-5-aminopyridine (0.5 gram) and 2,6-dichlorobenzoyl isocyanate (0.5 gram) were mixed in ethyl acetate, and the reaction mixture stirred overnight (about 18 hours) at room temperature. Solvent was removed by evaporation and the product residue crystallized from ethyl acetate-hexanes, yield 0.6 gram, m.p., 146-148 C. Calc. for C15 H10 Cl2 F3 N3 O3: C, 44.14; H, 2.47; N, 10.30. Found: C, 44.36; H, 2.54; N, 10.03.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 72617-82-4, 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine.

Reference:
Patent; Eli Lilly and Company; US4173639; (1979); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem