Adding a certain compound to certain chemical reactions, such as: 1197-10-0, 6-(Hydroxymethyl)picolinic acid, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 1197-10-0, blongs to pyridine-derivatives compound. Product Details of 1197-10-0
To a solution of 6-(hydroxymethyl)-2-pyridinecarboxylic acid (500 mg) in chloroform (10 ml) and DMF (0.1 ml) was added thionyl chloride (1 ml) and the mixture heated at 65 ¡ãC for 1 h. The solvent was removed in vacuo and the residue was azeotroped with chloroform (5 ml) then dried on a high vacuum line for 30 min to afford an orange oil (650 mg), presumed to be 6-(chloromethyl)-2-pyridinecarbonyl chloride.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1197-10-0, its application will become more common.
Reference:
Patent; GLAXO GROUP LIMITED; BALDWIN, Ian, Robert; DOWN, Kenneth, David; FAULDER, Paul; GAINES, Simon; HAMBLIN, Julie, Nicole; LE, Joelle; LUNNISS, Christopher, James; PARR, Nigel, James; RITCHIE, Timothy, John; ROBINSON, John, Edward; SIMPSON, Juliet, Kay; SMETHURST, Christian, Alan, Paul; WO2011/67364; (2011); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem