Adding a certain compound to certain chemical reactions, such as: 84487-15-0, 2-Bromo-5-nitropyridin-4-amine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 84487-15-0, blongs to pyridine-derivatives compound. SDS of cas: 84487-15-0
Step 2. Methyl 3- [ (4-amino-5-nitro-2-pyridinyl) oxy] benzoate Under nitrogen, to a solution of 2-bromo-5-nitro-4-pyridinamine (3.67g, 16.8 mmol) and methyl 3-hydroxybenzoate (2.82 g, 18.5 mmol) in DMF (100 mL), was added NaH (810 mg, 60% suspension, 20.2 mmol). 5 min later, the reaction mixture was heated to 65 C. The reaction mixture was concentrated, taken up in EtOAC, washed with NaOH solution (1. ON), saturated NH4C1 solution and brine, dried over Na2S04, filtered and concentrated to afford the title compound, which was used directly to next step without further purification.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,84487-15-0, its application will become more common.
Reference:
Patent; GLAXO GROUP LIMITED; WO2005/37197; (2005); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem