A new synthetic route of 58327-75-6

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 58327-75-6, 3-Aminothieno[2,3-b]pyridine-2-carboxylic acid, other downstream synthetic routes, hurry up and to see.

Reference of 58327-75-6, Adding some certain compound to certain chemical reactions, such as: 58327-75-6, name is 3-Aminothieno[2,3-b]pyridine-2-carboxylic acid,molecular formula is C8H6N2O2S, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 58327-75-6.

General procedure: To the solution of appropriate 2-aminobenzoic acid in dried THF or 1,4- dioxane was added triphosgene (0.35 eq). The mixture was stirred under reflux for 4-8 hrs. Then the solvent was removed in vacuo to give the isotaic anhydride as a solid in theoretical yield. 1H NMR indicated the product was of sufficient purity and was used in the next step without further purification.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 58327-75-6, 3-Aminothieno[2,3-b]pyridine-2-carboxylic acid, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Huang, Guozheng; Roos, Dominika; Stadtmueller, Patricia; Decker, Michael; Tetrahedron Letters; vol. 55; 26; (2014); p. 3607 – 3609;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem