Synthetic Route of 55052-27-2 ,Some common heterocyclic compound, 55052-27-2, molecular formula is C7H5ClN2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
At room temperature, concentrated aqueous ammonia (40 mL) was added drop-wise to 6-chloro-7-azaindole (3.20 g, 0.024mol), after the tube is heated, the reaction is heated at 120 C for 5h. The reaction is complete, cooling, filter and then obtained a brown solid product (2.00 g, 72%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,55052-27-2, its application will become more common.
Reference:
Patent; Ding Min; (8 pag.)CN108997343; (2018); A;,
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