Introduction of a new synthetic route about 2-Acetyl-6-bromopyridine

With the rapid development of chemical substances, we look forward to future research findings about 49669-13-8.

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 49669-13-8, name is 2-Acetyl-6-bromopyridine. This compound has unique chemical properties. The synthetic route is as follows. Quality Control of 2-Acetyl-6-bromopyridine

A solution of l-(6-bromopyridin-2-yl)ethanone (2.9636 g, 14.82 mmol) in methanol (40 mL) at 0C was charged with sodium borohydride (1.682 g, 44.4 mmol) and then allowed to warm to room temperature. After 2.5 hours, the reaction mixture was diluted with dichloromethane (60 mL) and water (60 mL) and the layers were separated. The organic layer was dried over sodium sulfate, filtered, and concentrated to yield the title compound. Calc’d for C7H9BrNO [M+H]+: 204, Found: 204.

With the rapid development of chemical substances, we look forward to future research findings about 49669-13-8.

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Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem