Electric Literature of 15103-48-7, Adding some certain compound to certain chemical reactions, such as: 15103-48-7, name is Pyridine-2-sulfonic acid,molecular formula is C5H5NO3S, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 15103-48-7.
Preparation 99 To a solution of 4-hydroxy-1-[4,5-bis(4-methylphenyl)oxazol-2-yl)butan-1-one (0.78 g) and triethylamine (2 ml) in DMSO (10 ml) was added a solution of pyridinesulfonic acid (1.16 g) in DMSO (4 ml) at room temperature. After being stirred for 20 minutes at the same temperature, the mixture was partitioned between ethyl acetate and water. The organic layer was washed with 1M-HCl, water and brine. The dried solvent was evaporated in vacuo and the residue was purified by chromatography on silica gel to give 1-[4,5-bis(4-methylphenyl)oxazol-2-yl)butan-1,4-dione (0.22 g). MS (m/z): 334 (M+ +1) IR (Nujol): 1735, 1690 cm-1 NMR (CDCl3, delta): 2.38 (3H, s), 2.40 (3H, s), 2.97 (2H, t, J=6.4 Hz), 3.47 (2H, t, J=6.4 Hz), 7.17-7.26 (4H, m), 7.53-7.59 (4H, m), 9.88 (1H, s)
According to the analysis of related databases, 15103-48-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Fujisawa Pharmaceutical Co., Ltd.; US5972965; (1999); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem