Application of 10177-08-9 , The common heterocyclic compound, 10177-08-9, name is 2-Oxo-5-phenyl-1,2-dihydropyridine-3-carboxylic acid, molecular formula is C12H9NO3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
EXAMPLE 22 5-Phenyl-2(1H)-pyridinone In the manner described in Example 20, a mixture of 12.4 g. of 1,2-dihydro-2-oxo-5-phenyl-3-pyridinecarboxylic acid (prepared as described in Example 15) and 50 ml. of quinoline yields 8.8 g. of the product of the Example as a gray solid, m.p. 173°-177° C.
The synthetic route of 10177-08-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; American Cyanamid Company; US4209626; (1980); A;; ; Patent; American Cyanamid Company; US4242515; (1980); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem