Analyzing the synthesis route of 5-Bromo-3-fluoropicolinonitrile

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 886373-28-0, 5-Bromo-3-fluoropicolinonitrile, other downstream synthetic routes, hurry up and to see.

Electric Literature of 886373-28-0, Adding some certain compound to certain chemical reactions, such as: 886373-28-0, name is 5-Bromo-3-fluoropicolinonitrile,molecular formula is C6H2BrFN2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 886373-28-0.

Cone. HCl (300 mL) were added to 5-Bromo-3-fluoro-pyridine-2-carbonitrile (21.0 g,0.11 mol) and stirred over night at 600C. After evaporation ether was added and the suspension was stirred for additional time. The solid was collected and dried. The crude product was used without any further purification. MS (m/z): 219.8 [M+H*]

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 886373-28-0, 5-Bromo-3-fluoropicolinonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; JERINI AG; WO2009/36996; (2009); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem