Adding a certain compound to certain chemical reactions, such as: 64188-97-2, 3-Aminoisonicotinamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, SDS of cas: 64188-97-2, blongs to pyridine-derivatives compound. SDS of cas: 64188-97-2
To a suspension of 3-amino-2-carboxamide (1.0 eq) and methyl 2- (chlorocarbonyl)benzofuran-7-carboxylate (1.5 eq) in tetrahydrofuran was added N,N- diisopropylethylamine (3.0 eq) dropwise. The mixture was allowed to stir for 1 hour and concentrated in vacuo to afford methyl 2-((4-carbamoylpyridin-3- yl)carbamoyl)benzofuran-7-carboxylate as a crude product. The residue was used in the next step without further purification
At the same time, in my other blogs, there are other synthetic methods of this type of compound,64188-97-2, 3-Aminoisonicotinamide, and friends who are interested can also refer to it.
Reference:
Patent; DONG-A SOCIO HOLDINGS CO., LTD.; KIM, Myeong-seop; PARK, Taesun; YOON, Taeyoung; YANG, Seung Min; KIM, Hae-Sun; KIM, Jun Gyu; (285 pag.)WO2016/68580; (2016); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem