In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1539-42-0, name is Bis(pyridin-2-ylmethyl)amine, the common compound, a new synthetic route is introduced below. Computed Properties of C12H13N3
The synthesis followed a modified literature procedure [35]. Amixture of DPA (4.21 g, 20.68 mmol) and triethylamine (4.18 g,41.3 mmol) was dissolved in THF and added dropwise to a solution of 2,6-bis(chloromethyl)-4-methylphenol (2.12 g, 10.3 mmol) in THF at 0C. After the complete addition of the DPA mixture the solution was warmed up to room temperature and left stirring for 4 days. The triethylamine salt precipitate was removed by filtration and washed 3 times with THF, and the combined filtrates were concentrated under vacuum. The residue was dissolved in 50 ml of water and extracted with CH2Cl2 (3¡Á50 ml). The extracts were combined, dried with MgSO4 and the solvent was removed under vacuum. The product was obtained as a yellow oily residue. Yield: 5.24 g (95.6%). 1H NMR (CDCl3): delta 8.42 (4H, m), 7.68 (m, 4H), 7.53 (dd, J=7.8, 3.2, 4H) 7.22 (m, 4H), 6.92 (d,J=3.2, 2H) 3.79 (d, J=3.3, 8H) 3.71 (d, J=3.2, 4H) 2.19 (d,J=3.3, 3H)
The synthetic route of 1539-42-0 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Bedin, Michele; Agarwala, Hemlata; Marx, Jennifer; Schuenemann, Volker; Ott, Sascha; Thapper, Anders; Inorganica Chimica Acta; vol. 490; (2019); p. 254 – 260;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem