The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 573762-62-6, name is 5-Amino-3-(trifluoromethyl)picolinonitrile. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: 573762-62-6
SM3 (20 g) and MeCN (300 mL) were added into a four-necked round bottom flask equipped with a mechanical stirrer and a thermometer at 20-30 C. under nitrogen followed by cooling to 0-10 C. Thiophosgene (13.7 mL) was added and the mixture was warmed to 20-30 C. After the reaction was completed, the reaction mixture was cooled to 0-10 C. and added saturated NaHCO3 to adjust the pH value to 6-7. The organic layer was separated and concentrated to dryness. The compound of Formula III was obtained (24.93 g) in 100% yield as the brown oil.
With the rapid development of chemical substances, we look forward to future research findings about 573762-62-6.
Reference:
Patent; ScinoPharm Taiwan, Ltd.; Chen, Shang-Hong; Guo, Jiunn-Cheh; Shih, Wen-Li; (12 pag.)US2018/201601; (2018); A1;,
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