Introduction of a new synthetic route about 2-(Trifluoromethyl)nicotinaldehyde

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,116308-35-1, its application will become more common.

Adding a certain compound to certain chemical reactions, such as: 116308-35-1, 2-(Trifluoromethyl)nicotinaldehyde, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 116308-35-1, blongs to pyridine-derivatives compound. COA of Formula: C7H4F3NO

General procedure: The appropriate substituted pyridine aldehyde (10 mmol) was dissolved in ethanol (20 mL) and sodium metabisulfite (15 mmol) in 5 mL water was added in portion over 5 minutes. The reaction mixture was stirred at room temperature for 1 h, and subsequently stirred at 4C overnight and the formed precipitate was filtered and dried to get sodium bisulfite adducts.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,116308-35-1, its application will become more common.

Reference:
Article; Ali, Mohamed Ashraf; Osman, Hasnah; Kumar, Raju Suresh; Almansour, Abdulrahman I.; Arumugam, Natarajan; Masand, Vijay H.; Panneerselvam, Theivendren; Letters in drug design and discovery; vol. 13; 7; (2016); p. 691 – 696;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem