Adding a certain compound to certain chemical reactions, such as: 25194-01-8, 2,6-Dichloro-4-nitropyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Product Details of 25194-01-8, blongs to pyridine-derivatives compound. Product Details of 25194-01-8
REFERENCE SYNTHESIS EXAMPLE 1 Synthesis of 2,6-dichloro-4-methoxypyridine used in the Synthesis example 6 To a tetrahydrofuran solution containing methanol (0.37 g, 0.0104*1.1 mol), sodium hydride (0.44 g, (ca.60% in mineral oil), 0.0104*1.05 mol) was added. Then 2,6-dichloro-4-nitropyridine (2.00 g, 0.0104 mol) was added thereto and the mixture was stirred for about 2 hours at room temperature. After it was confirmed that there was no bubbling with the addition of methanol (0.5 g), the mixture was stirred for about 1 hour. The reaction solution was partitioned between ethyl acetate and water. The obtained organic layer was washed successively with aqueous saturated sodium hydrogen carbonate and aqueous saturated sodium chloride, then dried over anhydrous sodium sulfate and concentrated to obtain the end product which was almost pure. Yield: 1.63 g (88%). Solid. Melting point: 94-96 C. 1 H-NMR (60 MHz, CDCl3, delta): 3.79(3H,s), 6.70(2H,s).
The synthetic route of 25194-01-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Kureha Kagaku Kogyo Kabushiki Kaisha; US5624942; (1997); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem