As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1033610-45-5, name is 4-Bromo-3,5-dimethoxypyridine, molecular formula is C7H8BrNO2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Recommanded Product: 1033610-45-5
4-bromo-3,5-dimethoxypyridine of structural formula 2 (440 mg, 2.0 mmol, 1.0 equiv.) was dissolved in 2 mL of an acetic acid solution of 33% by mass of hydrogen bromide. Heat to 130 C and react for 24 hours. After the reaction was completed, a 10% aqueous sodium hydrogencarbonate solution was added. After the workup, 335 mg of the crude product was obtained. Since the structural formula 3 is easily decomposed in the air, the crude product was used directly in the next reaction.
With the rapid development of chemical substances, we look forward to future research findings about 1033610-45-5.
Reference:
Patent; Chongqing University; Li Yang; Chen Di; (11 pag.)CN109836446; (2019); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem