In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 94170-15-7, name is 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbaldehyde, the common compound, a new synthetic route is introduced below. Safety of 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbaldehyde
Intermediate 2-11 (30 mg, 0.087 mmol) was dissolved in DCM (2 mL)4-Aldehyde-1-methylpyridine-2(1H)-one (14.3 mg, 0.104 mmol), NaBH (OAc) 3 (46.1 mg, 0.218 mmol).Stir at room temperature overnight.TLC monitors the reaction,Add saturated aqueous sodium bicarbonate (5 mL),Extracted with DCM (3 x 10 mL),Combine the organic phase,Wash with water (2 × 5mL),Dry over anhydrous sodium sulfate,filter,concentrate,The crude product was purified by silica gel column chromatography (DCM: MeOH=200:1-20:1)White solid (5.8 mg, yield: 14.5%).
The synthetic route of 94170-15-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Nanjing Yaojie Good Health Biological Technology Co., Ltd.; Wu Yongqian; Wang Lin; Yang Xiaoju; Tian Yuwei; (46 pag.)CN108341819; (2018); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem