Electric Literature of 884494-35-3, Adding some certain compound to certain chemical reactions, such as: 884494-35-3, name is 2-Chloro-5-fluoropyridin-3-ol,molecular formula is C5H3ClFNO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 884494-35-3.
Preparation 222 2-chloro-5-fluoro-3-methoxypyridine 2-chloro-5-fluoro-3-methoxypyridine (1.8 g, 72%) was prepared in an analogous manner to Preparation 153 using 2-chloro-5-fluoropyridin-3-ol (2.3 g, 16 mmol) and methanol (5 g, 156 mmol). 1H NMR (CDCl3, 400 MHz): delta 7.89 (d, J=2.70 Hz, 1H), 7.00 (dd, J=2.5, 9.1 Hz, 1H), 3.93 (s, 3H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 884494-35-3, 2-Chloro-5-fluoropyridin-3-ol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Pfizer Inc.; Strohbach, Joseph Walter; Akama, Tsutomu; Blakemore, David Clive; Jacobs, Robert Toms; Jones, Peter; Limburg, David Christopher; Oderinde, Martins Sunday; Perry, Matthew Alexander; Plattner, Jacob John; Torella, Rubben Federico; Zhou, Yasheen; Yeoh, Thean Yeow; (200 pag.)US2020/108083; (2020); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem