Introduction of a new synthetic route about 56826-61-0

Statistics shows that 56826-61-0 is playing an increasingly important role. we look forward to future research findings about (2-Methylpyridine-3-yl)methanol.

Electric Literature of 56826-61-0, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.56826-61-0, name is (2-Methylpyridine-3-yl)methanol, molecular formula is C7H9NO, molecular weight is 123.1525, as common compound, the synthetic route is as follows.

(a) 2-methyinicotinaidehyde: To a stirred solution of (2-methyipyridin-3-yl)methanoi (200 mg, 1.6 mmol) in CH2CI2 (10 mL) was added Mn02 (200 mg, 2.3 mmol). The mixture wasrefluxed overnight under rutrogcn. The solid was removed by fihration. After removal ofsolvent, the crude product was purified by silica gel column chromotography (petroleumether/EtOAc = i/i) to give the title compound (120 rug, 60%) as a colorless liquid .LCMS-PI:122.0 [M+H]t R = 0.344 miii.

Statistics shows that 56826-61-0 is playing an increasingly important role. we look forward to future research findings about (2-Methylpyridine-3-yl)methanol.

Reference:
Patent; TEMPERO PHARMACEUTICALS, INC.; BALOGLU, Erkan; GHOSH, Shomir; LOBERA, Mercedes; SCHMIDT, Darby, R.; WO2013/19626; (2013); A1;,
Pyridine – Wikipedia,
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