Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Application In Synthesis of 31181-90-5.
Bailey, Andrew;Lister, Andrew;Moss, Thomas;Scott, James S.;Wu, Ye;Lamont, Scott G. research published 《 Synthesis of trans 8-substituted-6-phenyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolines using a Pictet-Spengler approach》, the research content is summarized as follows. Two complementary approaches for the synthesis of trans 8-substituted-6-phenyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolines I [R = iBu, CH2CHF2, CH2CF3, (1-fluorocyclopropyl)methyl, CH2C(Me)2F; Ar = 4-BrC6H4, 5-Br-2-pyridyl, 4-Br-3-F-C6H3, 4_Br-2,6-di-FC6H2, 4-Br-2-MeOC6H3] was reported. The first method, directly from α-Me substituted indazole ethanamines, was successful but had limited substrate scope. The second method utilized a modified Pictet-Spengler cyclization reaction on an aniline substrate followed by late stage construction of the indazole ring and was more versatile in terms of substrate scope.
Application In Synthesis of 31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.
5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.