At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Computed Properties of 5315-25-3.
Dash, Dibyajit;Baral, Minati;Kanungo, B. K. research published 《 Synthesis of a new tetradentate chelator with 1-Hydoroxy-2(1H)-pyridinone (HOPO) as chelating unit: Interaction with Fe(III), solution thermodynamics and DFT studies》, the research content is summarized as follows. 1,2-Hydroxypyridinone (1,2-HOPO) forms very stable transition metal complexes that may be useful in various ways, among these the iron complexes have been long used for the treatment of iron overload diseases like β-Thalassemia. A new tetradentate chelator, 1-hydroxy-N-[3-[2-[2-[3-[(1-hydroxy-6-oxo-pyridine-2-carbonyl)amino]propoxy]ethoxy]ethoxy]propyl]-6-oxo-pyridine-2-carboxamide (L) having two 1,2-HOPO units with long chain amine backbone has been synthesized and characterized through various techniques like TLC, solubility, m.p., FT-IR, 1H NMR, 13C NMR, ESI-MS, UV-Vis and emission spectroscopy. The protonation constants of the ligand were determined by both potentiometrically as well as spectrophotometrically in aqueous medium at 25° ±1°C. The solution thermodn. of the ligand its Fe(III) complexes in aqueous solution were also studied. The pKa values for ligand are found to be 7.34 and 6.06 and the formation constant of metal complex (M2L3) is found to be logβ230 = 42.45. To support the exptl. data, theor. calculation at DFT level of theory was done using GGA (Gradient Generalized Approximation) with BLYP functional and DZP basis set. The results of calculated thermodn. properties suggest that, ΔG follows the same trend of protonation as determined by potentiometry and spectrophotometry. Studies of the DFT optimized structures of LH2, LH– shows that, there is π stacking interaction between the hydroxypyridinone rings in the species and the intramol. π-stacking interaction decreases as the distance between two pyridine ring increases upon deprotonation and was found to be 2.7, 3.2 and 14.6 Å for LH2, LH– and L-2 resp.
Computed Properties of 5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.