At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Related Products of 16133-25-8.
Huang, Binbin;Yang, Chao;Zhou, Jia;Xia, Wujiong research published 《 Electrochemically generated N-iodoaminium species as key intermediates for selective methyl sulphonylimination of tertiary amines》, the research content is summarized as follows. A straightforward protocol for approaching N-sulfonylamidines (E/Z)-RS(O)2N=CHN(R1)(R2) (R = Me, 2-fluorophenyl, thiophen-2-yl, etc.; R1 = Me; R2 = Et, cyclohexyl, benzyl, etc.; R1R2 = -(CH2)5-, -(CH2)2O(CH2)2-) and I via an electricity-driven, iodine-mediated cross dehydrogenative condensation (CDC) between sulfonamides RS(O)2NH2 and tertiary amines CH3N(R1)(R2), which features exclusive N-CH3 selectivity for the amine partners was reported. Mechanistic studies indicate that an in situ generated N-iodoaminium species serves as the key intermediate.
Related Products of 16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.