Lecroq, William;Schleinitz, Jules;Billoue, Mallaury;Perfetto, Anna;Gaumont, Annie-Claude;Lalevee, Jacques;Ciofini, Ilaria;Grimaud, Laurence;Lakhdar, Sami published 《Metal-Free Deoxygenation of Amine N-Oxides: Synthetic and Mechanistic Studies》. The research results were published in《ChemPhysChem》 in 2021.Computed Properties of C6H4N2 The article conveys some information:
An unprecedented combination of light and P(III)/P(V) redox cycling for the efficient deoxygenation of aromatic amine N-oxides was reported. Moreover, a large variety of aliphatic amine N-oxides was easily deoxygenated by using only phenylsilane. These practically simple approaches proceeded well under metal-free conditions, tolerated many functionalities and were highly chemoselective. Combined exptl. and computational studies enabled a deep understanding of factors controlling the reactivity of both aromatic and aliphatic amine N-oxides. To complete the study, the researchers used 3-Cyanopyridine (cas: 100-54-9) .
3-Cyanopyridine(cas: 100-54-9) has been shown to have a number of pharmacological effects: it inhibits the production of prostaglandin E2 and nitric oxide in congestive heart failure patients; it prevents the formation of diazonium salt from benzene and nitrogen dioxide; it inhibits the growth of tumor cell lines; and it protects mice from radiation injury by scavenging reactive oxygen species. Computed Properties of C6H4N2