Yuan, Qianjia; Sigman, Matthew S. published the artcile< Palladium-Catalyzed Enantioselective Relay Heck Arylation of Enelactams: Accessing α,β-Unsaturated δ-Lactams>, Related Products of 1416819-91-4, the main research area is oxidative relay Heck arylation arylboronic acid lactam; substituted lactam asym preparation.
In this Communication, the construction of chiral α,β-unsaturated δ-lactams, e.g. I, widely used as pharmacophores, in high yields and excellent enantioselectivities using an oxidative relay Heck arylation reaction is reported. This strategy also allows facile access to 7-substituted α,β-unsaturated ε-lactam products and δ-lactams containing a tetrasubstituted nitrogen-bearing stereocenter.
Journal of the American Chemical Society published new progress about Arylboronic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 1416819-91-4 belongs to class pyridine-derivatives, and the molecular formula is C13H15F3N2O, Related Products of 1416819-91-4.