Adding a certain compound to certain chemical reactions, such as: 5349-17-7, 2-Bromo-1-(pyridin-4-yl)ethanone hydrobromide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, HPLC of Formula: C7H7Br2NO, blongs to pyridine-derivatives compound. HPLC of Formula: C7H7Br2NO
EXAMPLE 13 [6-CHLORO-3-(1H-1,2,3,4-TETRAZOL-5-YLMETHYL)-1H-INDOL-2-YL](4-PYRIDINYL)METHANONE The title compound was prepared according to the procedure described in step 5 of Example 1 from N-(5-chloro-2-{(E)-2-[1-(2-cyanoethyl)-1H-1,2,3,4-tetrazol-5-yl]ethenyl}phenyl)benzenesulfonamide (Example 1, step 4) and 4-bromoacetylpyridine hydrobromide (L. W. Deady, M. S. Stanborough, Aust. J. Chem., 1981, 34 , 1295). MS (EI) m/z: 338 (M+). IR (KBr) nu: 3246, 2870, 1637, 1526, 1439, 1323, 1248, 943, 841. 1H-NMR (DMSO-d6) delta: 11.92 (1H, s), 8.80 (2H, d, J=4.5 Hz), 7.68 (1H, d, J=8.7 Hz), 7.63 (2H, d, J=4.5 Hz), 7.51 (1H, d, J=1.8 Hz), 7.15 (1H, dd, J=1.8, 8.7 Hz), 4.58 (2H, s).
The synthetic route of 5349-17-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; PFIZER INC.; EP1065206; (2001); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem