Yao, Kun; Yuan, Qianjia; Qu, Xingxin; Liu, Yangang; Liu, Delong; Zhang, Wanbin published the artcile< Pd-catalyzed asymmetric allylic substitution cascade using α-(pyridin-1-yl)-acetamides formed in situ as nucleophiles>, Related Products of 581-47-5, the main research area is chiral piperidinyl amino acid enantioselective preparation.
Chiral piperidine-containing amino acid derivatives, e.g., I, were synthesized via Pd-catalyzed asym. allylic substitution cascade reaction of cinnamyl carbonates, chloroacetamides and substituted pyridines. In situ generated α-(pyridin-1-yl)-acetamides were used as nucleophiles in this cascade reaction. The products could be easily converted into potential bioactive compounds, unnatural chiral amino acids and dipeptides. Pd-catalyzed asym. allylic substitution cascade using α-(pyridin-1-yl)-acetamides formed in situ as nucleophiles.
Chemical Science published new progress about Amides Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 581-47-5 belongs to class pyridine-derivatives, and the molecular formula is C10H8N2, Related Products of 581-47-5.