Azum, Naved; Rub, Malik Abdul; Alfaifi, Sulaiman Yahya; Asiri, Abdullah M. published the artcile< Interaction of diphenhydramine hydrochloride with cationic and anionic surfactants: mixed micellization and binding studies>, Product Details of C21H38ClN, the main research area is diphenhydramine hydrochloride cationic anionic surfactant mixed micellization binding study; binding studies; cetylpyridinium chloride; diphenhydramine hydrochloride; mixed micellization; sodium dodecyl sulfate.
The focus of the present work is to evaluate the interactions of an anti-allergic drug (diphenhydramine hydrochloride, DPH) with anionic (sodium dodecyl sulfate, SDS) and cationic (cetylpyridinium chloride, CPC) surfactants in the aqueous medium. The mixed micellization behavior and surface properties of drug-surfactant mixtures have been examined by surface tension measurements. Various theor. approaches were applied to explore the synergistic or non-ideal behavior of the current mixed systems. Furthermore, the binding studies of drug with surfactants have been elaborated by UV-visible spectroscopy. Benesi-Hildebrand (B-H) theory was used to compute stoichiometric ratio, binding constant, and free energy change for the drug-surfactant mixtures The outputs are deliberated taking into consideration the use of surfactants as capable drug delivery agents for DPH and hence advance bioavailability.
Polymers (Basel, Switzerland) published new progress about Absorption spectra. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Product Details of C21H38ClN.