Babaev, Eugene V.; Rybakov, Victor B. published the artcile< Phenacylation of 6-methyl-beta-nitropyridin-2-ones and further heterocyclization of products>, SDS of cas: 22280-62-2, the main research area is betanitropyridinone phenacylation; phenacylpyridone heterocyclization; 8-nitro-5-RO-indolizines; Phenacylation of beta-nitropyridin-2-ones; oxazole-pyrrole ring transformation.
Reaction between the derivatives of 6-methyl-beta-nitropyridin-2-one and phenacyl bromides was studied, and the yields observed were extremely low. The pyridones were converted via chloropyridines to methoxyderivatives, which were N-phenacylated. N-Phenacyl derivatives of 4,6-dimethyl-5-nitropyridin-2-one under the action of base gave 5-hydroxy-8-nitroindolizine and under acidic conditions gave 5-methyl-6-nitrooxazole[3,2-a]pyridinium salt, which underwent recyclization with MeONa to 5-methoxy-8-nitroindolizine.
Molecules published new progress about Acylation. 22280-62-2 belongs to class pyridine-derivatives, and the molecular formula is C6H7N3O2, SDS of cas: 22280-62-2.