Analyzing the synthesis route of 2-Aminonicotinic acid

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Electric Literature of 5345-47-1, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5345-47-1, name is 2-Aminonicotinic acid. This compound has unique chemical properties. The synthetic route is as follows.

(A) EtOH (500 mL) was added to 2-amino-nicotinic acid (25 g), followed by H2SO4 (25 mL, cone), and the mixture stirred at 75C overnight. The reaction mixture was then redissolved in H2O, neutralized with Na2CO3 (aq), and the resulting precipitate filtered and dried to provide 2-amino-nicotinic acid ethyl ester, which was used without further purification.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 5345-47-1, 2-Aminonicotinic acid.

Reference:
Patent; F. HOFFMANN-LA ROCHE AG; BUETTELMANN, Bernd; GOYAL, Bindu; PALMER, Wylie Solang; WO2010/97335; (2010); A1;,
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