In 1970,Journal of the Chemical Society [Section] B: Physical Organic included an article by Campbell, Arthur Derek; Chooi, S. Y.; Deady, L. W.; Shanks, R. A.. Safety of Methyl 5-methoxypicolinate. The article was titled 《Transmission of substituent effects of pyridines. I. Alkaline hydrolysis of some 3- and 4-substituted methyl pyridinecarboxylates》. The information in the text is summarized as follows:
The alk. hydrolysis of Me 5-(X-substituted)picolinates, Me 4-(X-substituted)picolinates, and Me 5-(X-substituted)nicotinates (X = NO2, Br, H, MeO, or Me2N) in methanol-water (85% wt/wt) is reported. In each series, the effect of the substituent and ring N are additive and the rates may be correlated with Hammett σm and σp values. In the experiment, the researchers used many compounds, for example, Methyl 5-methoxypicolinate(cas: 29681-39-8Safety of Methyl 5-methoxypicolinate)
Methyl 5-methoxypicolinate(cas: 29681-39-8) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Safety of Methyl 5-methoxypicolinate