Guo, Yuanqiang; Cao, Yunpeng; Song, Hongjian; Liu, Yuxiu; Wang, Qingmin published an article in 2021. The article was titled 《Photoredox relay-catalyzed gem-difluoroallylation of alkyl iodides》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Reference of Pyridin-3-ylboronic acid The information in the text is summarized as follows:
Herein, a new example of relay catalysis, using a combination of Mn2(CO)10 and an iridium-based photocatalyst, is reported. In this relay catalytic reaction, the Mn catalyst and iridium-based photocatalyst catalyze the reaction at different stages in the desired sequence under the same reaction conditions, and do not inhibit each other. This convenient method transforms a broad scope of alkyl iodides RI (R = iso-Pr, cyclopentyl, 4-methoxyphenethyl, morpholino, etc.) into the corresponding gem-difluoroalkenes R1C(=CF2)CH2R (R1 = Ph, 2-naphthyl, pyridin-3-yl, etc.) via C(sp3)-C(sp3) bond construction. The protocol has good functional group tolerance and is suitable for the late-stage modification of multifunctional complex mols. In the experiment, the researchers used many compounds, for example, Pyridin-3-ylboronic acid(cas: 1692-25-7Reference of Pyridin-3-ylboronic acid)
Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Reference of Pyridin-3-ylboronic acid