Adding a certain compound to certain chemical reactions, such as: 15855-06-8, 2-Chloro-6-methoxypyridine-4-carboxylic Acid, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Quality Control of 2-Chloro-6-methoxypyridine-4-carboxylic Acid, blongs to pyridine-derivatives compound. Quality Control of 2-Chloro-6-methoxypyridine-4-carboxylic Acid
To a suspension of 2-chloro-6-methoxy-isonicotinic acid (2.00 g, 10.7 mmol) in MeOH (100 mL), H2SO4 (2 mL) is added. The mixture is stirred at 65 C. for 20 h. The solution is cooled to rt. A precipitate forms. The solid material is collected, washed with MeOH and dried to give 2-chloro-6-methoxy-isonicotinic acid methyl ester (1.66 g) as a white solid; LC-MS: tR=1.29 min; [M+1]+=202.00.
The synthetic route of 15855-06-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Actelion Pharmaceuticals Ltd.; US2010/63108; (2010); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem