《Imaging and therapeutic applications of Zn(II)-cryptolepine-curcumin molecular probes in cell apoptosis detection and photodynamic therapy》 was written by Qin, Qi-Pin; Wei, Zu-Zhuang; Wang, Zhen-Feng; Huang, Xiao-Ling; Tan, Ming-Xiong; Zou, Hua-Hong; Liang, Hong. Electric Literature of C12H13N3 And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:
Novel red Zn(II) complex-based fluorescent probes featuring cryptolepine-curcumin derivatives, namely, [Zn(BQ)Cl2] (BQ-Zn) and [Zn(BQ)(Cur)]Cl (BQCur-Zn), were developed for the simple and fluorescent label-free detection of apoptosis, an important biol. process. The probes could synergistically promote mitochondrion-mediated apoptosis and enhance tumor therapeutic effects in vitro and vivo. The experimental part of the paper was very detailed, including the reaction process of Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Electric Literature of C12H13N3)
Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. The compound is a tridentate ligand in coordination chemistry and commonly used to produce Zn-based chemosensors/probes, such as Zinpry.Electric Literature of C12H13N3