《Facile Synthesis of Amphiphilic Bottlebrush Block Copolymers Bearing Pyridine Pendants via Click Reaction from Protected Alkyne Side Groups》 was published in Macromolecules (Washington, DC, United States) in 2020. These research results belong to Kim, Myung-Jin; Yu, Yong-Guen; Chae, Chang-Geun; Seo, Ho-Bin; Lee, Jae-Suk. Reference of 2-(Bromomethyl)pyridine hydrobromide The article mentions the following:
We present the facile synthetic platform for the production of amphiphilic bottlebrush block copolymers bearing pyridine pendants through combination of living anionic polymerization (LAP), ring-opening metathesis polymerization (ROMP), and copper-catalyzed azide-alkyne cycloaddition (CuAAC). ω-Norbornenyl poly(4-((trimethylsilyl)ethynyl)styrene) (NBPTMSESt) with controlled mol. weights (Mn = 3-4 kDa) and low dispersity (D = 1.03-1.08) was synthesized by LAP and the subsequent end-capping reaction with exo-N-(n-decyl-10-phenylacrylate)-5-norbornene-2,3-dicarboximide. Well-defined bottlebrush block copolymers (Mn = 134-548 kDa, D = 1.04-1.14) were achieved through sequential ROMP of ω-norbornenyl polystyrene with NBPTMSESt and subsequently deprotected with the clickable alkyne group. Amphiphilic bottlebrush block copolymers were obtained by the click reaction of alkyne and azide functional pyridines in the presence of the organic-soluble catalyst/ligand system of CuBr(PPh3)3 and N,N,N’,N”,N”-pentamethyldiethylenetriamine. These polymers exhibited the three-dimensional ordered porous films through breath-figure self-assembly. The experimental part of the paper was very detailed, including the reaction process of 2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8Reference of 2-(Bromomethyl)pyridine hydrobromide)
2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Reference of 2-(Bromomethyl)pyridine hydrobromide