In 2019,Angewandte Chemie, International Edition included an article by Koniarczyk, J. Luke; Greenwood, Jacob W.; Alegre-Requena, Juan V.; Paton, Robert S.; McNally, Andrew. SDS of cas: 100-48-1. The article was titled 《A Pyridine-Pyridine Cross-Coupling Reaction via Dearomatized Radical Intermediates》. The information in the text is summarized as follows:
A pyridine-pyridine coupling reaction has been developed between pyridyl phosphonium salts and cyanopyridines using B2pin2 as an electron-transfer reagent. Complete regio- and cross-selectivity are observed when forming a range of valuable 2,4′-bipyridines. Phosphonium salts were found to be the only viable radical precursors in this process, and mechanistic studies indicate that the process does not proceed through a Minisci-type coupling involving a pyridyl radical. Instead, a radical-radical coupling process between a boryl phosphonium pyridyl radical and a boryl-stabilized cyanopyridine radical explains the C-C bond-forming step. In the experiment, the researchers used many compounds, for example, 4-Cyanopyridine(cas: 100-48-1SDS of cas: 100-48-1)
4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.SDS of cas: 100-48-1