Li, Xiaolan; Zhang, Xiuqi; Zhang, Fukuan; Luo, Xuzhong; Luo, Haiqing published the artcile< Construction of Pyridine Ring Systems by Mn(OAc)2-Promoted Formal Dehydrative Dehydroaromatizing [4+2] Cycloaddition of Enamides with Maleimides>, Product Details of C7H7NO, the main research area is pyrrolopyridine preparation; enamide maleimide formal dehydrative dehydroaromatizing cycloaddition manganese acetate promoted.
A Mn(OAc)2-promoted formal dehydrative dehydroaromatizing [4+2] cycloaddition of enamides with maleimides for the construction of pyridine rings to access the diverse synthetically valuable pyrrolo[3,4-c]-pyridine derivatives I [R = Ph, 4-FC6H4, 2-naphthyl, etc.; R1 = Me, Et, Bn, etc.] was reported. This protocol allowed two C-C bond formation for the assembly of pyridine derivatives from enamides synthesizable in two steps and inexpensive maleimides, which exhibited broad substrate scope and good functional group compatibility.
Advanced Synthesis & Catalysis published new progress about [4+2] Cycloaddition reaction. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Product Details of C7H7NO.