Some scientific research about 926294-07-7

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,926294-07-7, its application will become more common.

Application of 926294-07-7 ,Some common heterocyclic compound, 926294-07-7, molecular formula is C7H6BrNO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

A mixture of 6-bromo-4-methylpyridine-3-carboxaldehyde (1.53 g, 7.69 mmol), 4- hydroxy-benzoic acid methyl ester (1.22 g, 8.0 mmol) and K2CO3 (1.06 g, 7.69 mmol) in DMF (20 mL) was stirred at 125 C for 3 h. The mixture was cooled to room temperature and DMF EPO was removed. Aqueous work-up and purification by flash chromatography on silica gel (CH3OH/CH2C12, 1:50 in v/v) afforded 4-(5-formyl-4-methyl-pyridin-2-yloxy)-benzoic acid methyl ester as a white solid (0.524 g, 25%). 1H NMR (CDCl3) delta 2.68 (s, 3H), 3.92 (s, 3H), 6.84 (s, IH), 7.19-7.26 (m, 2H), 8.10-8.14 (m, 2H), 8.50 (s, IH), 10.11 (s, IH).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,926294-07-7, its application will become more common.

Reference:
Patent; ANORMED INC.; WO2007/22371; (2007); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem