Echterhoff, Antje K. C.; Yogendra, Sivathmeehan; Koesters, Jutta; Fischer, Roland; Weigand, Jan J. published the artcile< A versatile protocol for the synthesis of pyrazolyl-substituted pyridinium and guanidinium salts from pyridone and urea derivatives>, HPLC of Formula: 73018-09-4, the main research area is pyridinium pyrazolyl guanidinium triflate preparation crystal structure; tripyridyl phosphite preparation crystal structure.
The trication I was used as a convenient pyrazolyl-transfer reactant to convert 2-pyridone, 4-pyridone and urea derivatives such as benzimidazol-2-one and theobromine to their pyrazolyl substituted triflate salts, e.g., II. The conversion represented a new, efficient and highly functional group-compatible approach that yielded the desired products conveniently and in high yields. Typically the reaction proceeded via exchange of carbonyl oxygen atom of the substrate for pyrazolyl moiety. However, for the structurally related 3-hydroxypyridines, a different reaction pathway occurred giving tripyridyl phosphites, e.g., III which was explained by the lactam-lactim tautomerism of the substrate. The structural arrangements of most of the products were confirmed by X-ray crystallog. anal.
European Journal of Organic Chemistry published new progress about Crystal structure. 73018-09-4 belongs to class pyridine-derivatives, and the molecular formula is C5H4ClNO, HPLC of Formula: 73018-09-4.