Yang, Cheng; Xie, Hao published the artcile< Multiple fluorescence response behaviours to proteins/bacteria and selective antibacterial activity of cetylpyridinium chloride (CPC)-based cationic carbon dots>, Formula: C21H38ClN, the main research area is fluorescence cetylpyridinium chloride cationic carbon dot.
Direct interaction between carbon dots (CDs) and biomols. leads to changes in the chem. and phys. status as well as properties of CDs, which can have various biol. and biomedical applications. In this work, the surface of CDs was modified with cetylpyridinium chloride (CPC) to facilitate interactions between CDs and biomols. Multiple fluorescence response behaviors of CPC-based CDs were observed towards several proteins (bovine serum albumin, lysozyme, protamine, and Hb) and bacterial cells (Escherichia coli and Staphylococcus aureus). Electrostatic attraction and hydrogen bonding were involved in inducing aggregation of CDs and fluorence enhancement. An inner filter effect might also occur to reduce fluorescence of CDs when interacting with proteins. Selective antibacterial activity of CPC-based CDs was observed towards Gram pos. bacterium Staphylococcus aureus. This work provides potential to develop CD-based techniques for detecting and visualizing proteins/bacteria as well as selective antibacterial agents towards Gram-pos. bacteria.
RSC Advances published new progress about Antibacterial agents. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Formula: C21H38ClN.