Izzo, Francesco; Mercurio, Mariano; de Gennaro, Bruno; Aprea, Paolo; Cappelletti, Piergiulio; Dakovic, Aleksandra; Germinario, Chiara; Grifa, Celestino; Smiljanic, Danijela; Langella, Alessio published the artcile< Surface modified natural zeolites (SMNZs) as nanocomposite versatile materials for health and environment>, COA of Formula: C21H38ClN, the main research area is zeolite nanocomposite ibuprofen sodium salt drug release surface modification; Bayesian information criterion; Emerging contaminant; Ibuprofen; NSAID; Nižný hrabovec; Non-linear regression; Sips; Surfactant; Toth; Zeolite.
The present research deals with the evaluation of a clinoptilolite-rich rock, occurring in the Nizny ‘Hrabovec deposit (Slovakia), for high-value technol. applications based on sorption and in vitro release of nonsteroidal anti-inflammatory drugs (i.e., ibuprofen sodium salt). This georesource was surface modified (SMNZ) using four cationic surfactants. Results demonstrate that ibuprofen sorption is very fast and SMZNs can sorb up to ~26 mg/g of drug as a function of the type of counterion and morphol. of surfactant, as well as the hydrophobicity and mol. structure of the drug. Maximum sorption capacities observed for all SMNZs are fully comparable to other adsorbent carriers usually used for removal of contaminants in wastewaters. Sorption of ibuprofen is controlled by a dual mechanism: external anionic exchange and partition into the hydrophobic portion of the patchy bilayer. A prompt drug release in simulated intestinal fluid (SIF) was also observed, making this natural material also suitable to provide rapid soothing effects in potential pharmacol. applications. Comparing the results of this study with other recent investigations, a good technol. performance of clinoptilolite-rich rock can be inferred despite the relatively low zeolite content (~56 weight%).
Colloids and Surfaces, B: Biointerfaces published new progress about Adsorption. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, COA of Formula: C21H38ClN.